石运伟，博士，副教授，硕士生导师。2012年博士毕业于南京大学，2022年-2023年在新加坡国立大学从事访学研究，现主要从事血管新生调控和神经损伤与修复相关病理药理研究。先后主持国家自然科学基金面上项目和制药企业药物研发等项目。以第一作者或通讯作者在血管、神经科学领域发表SCI论文10余篇，获授权发明专利2项。为多个SCI期刊邀请审稿人。承担《高级分子生物学》《生物化学》等课程授课。
专业研究领域
1、脑卒中疾病血管与神经病理机制
2、生理、病理状态血管与神经互作机制
3、血管与神经相关疾病防治活性物质的筛选及作用机理
联系邮箱：shiyunwei@ntu.edu.cn。
代表性论文
1.Shi YW #, Xu CC #, Sun CY #, Liu JX, Zhao SY, Liu D *, Fan XJ *, Wang CP *. GM1 ameliorates neuronal injury in rats after cerebral ischemia and reperfusion: potential contribution of effects on sptbn1-mediated signaling. Neuroscience 2024, 551: 103 - 118. (# Co-first author, * Corresponding author)
2.Sheng JJ #, Gong J #, Shi YW #, Wang X, Liu D *. MicroRNA-22 coordinates vascular and motor neuronal pathfinding via sema4 during zebrafish development. Open Biology 2022, 12: 210315.
3.Shi YW #, Jin Y#, Li X#, Chen C, Zhang ZH, Liu XY, Deng YJ, Fan XJ, Wang CP*. C5aR1 mediates the progression of inflammatory responses in the brain of rats in the early stage after ischemia and reperfusion. ACS Chemical Neuroscience 2021, 12: 3994 - 4006.
4.Shi YW #, Chen XY #, Liu JX, Fan XJ, Jin Y, Gu JX, Liang JL, Liang XM *, Wang CP *. Isoquercetin improves inflammatory response in rats following ischemic stroke. Frontiers in Neuroscience 2021, 15: 555543.
5.Liu C #, Zhao JX #, Zhang X #, Wei GY, Hao WJ, Wang X, Yang C, Shi YW *, Dong Liu *. Biomass-derived cellulose nanoparticles display considerable neurotoxicity in zebrafish. International Journal of Biological Macromolecules 2020, 165: 1783 - 1792.
6.Shi YW #, Wang XN #, Shi YY#, Zhang J, Zhao SY, Yin ZH, Xu GM, Duan XC, Guo ZM*, Liang XM*, Liu D*. Two compounds isolated from ganglioside GM1 promote angiogenesis in zebrafish. Journal of Cardiovascular Pharmacology 2019, 74: 71 - 79.
7.Shi YW #, Duan XC #, Xu GM #, Wang XN, Wei GY, Dong SK, Xie GC *, Liu D *, A ribosomal DNA-hosted microRNA regulates zebrafish embryonic angiogenesis. Angiogenesis 2019, 22: 211 - 221.
8.Shi YW #, Zhang XC #, Chen C, Tang M, Wang ZW, Liang XM *, Ding F *, Wang CP *. Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways. Brain, Behavior, and Immunity 2017, 66: 244 - 256.
9.Wang CP #, Shi YW #, Tang M, Zhang XC, Gu Y, Yun Liang XM *, Wang ZW *, Ding F *. Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats. Molecular Neurobiology 2017, 54: 2126 - 2142.
10.Shi YW #, Yuan W #, Wang X, Gong J, Zhu SX, Chai LL, Qi JL, Qin YY, Gao Y, Zhou YL, Fan XL, Ji CY, Wu JY, Wang ZW, Liu D *. Combretastatin a-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish, Scientific Reports 2016, 6: 30189.
