杨鹏翔,医学博士,副研究员,硕士生导师。获北京协和医学院-清华大学医学部博士学位,生物医学工程专业,研究方向为免疫生物材料。自2011年以来,先后在哈尔滨医科大学肿瘤防治研究所和南通大学神经再生重点实验室工作。近五年发表SCI论文10余篇,累计影响因子超过100分,总引用次数400余次,申请发明专利5项,授权1项。主持国家自然科学基金2项,黑龙江省自然科学基金优秀青年项目、黑龙江省应用技术与开发科技攻关项目、北京协和医学院创新基金项目等。
邮箱:yangpengxiang@ntu.edu.cn;yangpengxiang@163.com
代表性论著
1. Yang P, SongH, Qin Y, Huang P, Zhang C, Kong D*, Wang W*: Engineering Dendritic-Cell-Based Vaccines and PD-1 Blockade in Self-Assembled Peptide Nanofibrous Hydrogel to Amplify Antitumor T-Cell Immunity, Nano Letters 2018, 18(7): 4377-4385. (第一作者)
2. Yang P, SongH, Feng Z, Wang C, Huang P, Zhang C, Kong D*, Wang W*: Synthetic, Supramolecular, and Self-Adjuvanting CD8+ T-Cell Epitope Vaccine Increases the Therapeutic Antitumor Immunity, Advanced Therapeutics2019, 2 (7): 1900010. (第一作者)
3. Yang P, Cao X, Cai H, Feng P, Chen X, Zhu Y, Yang Y, An W, Yang Y*, Jie J*. The Exosomes Derived from CAR-T Cell Efficiently Target Mesothelin and Reduce Triple-negative Breast Cancer Growth. Cellular Immunology 2021, 360:104262. (第一作者)
4. Yang P, Cao X, Cai H, Chen X, Zhu Y, Yang Y, An W, Jie J. Upregulation of microRNA-155 Enhanced Migration and Function of Dendritic Cells in Three-dimensional Breast Cancer Microenvironment. Immunological Investigations, 2021, 50(8):1058-1071. (第一作者)
5. Jie J#, Mao D#, Cao J, Feng P, Yang P. Customized multifunctional peptide hydrogel scaffolds for CAR-T-cell rapid proliferation and solid tumor immunotherapy. ACS Applied Materials & Interfaces 2022; 14: 37514-37527. (通讯作者)
6. Yang P, Peng Y, Feng Y, Xu Z, Feng P, Cao J, Chen Y, Chen X, Cao X*, Yang Y*, Jie J*. Immune Cell-Derived Extracellular Vesicles – New Strategies in Cancer Immunotherapy. Frontiers in Immunology 2021,12 (5259). (第一作者)
7. Ma J#, Yang Y#, Huo D, Wang Z, Zhai X, Chen J, Sun H, An W, Jie J*, Yang P*: LincRNA-RoR/miR-145 Promote Invasion and Metastasis in Triple-negative Breast Cancer via Targeting MUC1. Biochemical and Biophysical Research Communications 2018, 500(3):614-620. (通讯作者)
8. Yang P, Yang Y, An W, Xu J, Zhang G, Jie J*, Zhang Q*: The Long Noncoding RNA-ROR Promotes the Resistance of Radiotherapy for Human Colorectal Cancer Cells by Targeting the p53/miR-145 Pathway. Journal of Gastroenterology and Hepatology 2017, 32(4):837-845. (第一作者)
9. Zhou, Y#, Wu, W#, Yang, P#, Mao, D*, Liu, B*. Near-infrared chemiluminescent nanoprobes for deep imaging and synergistic photothermal-nitric-oxide therapy of bacterial infection. Biomaterials 2022, 121693. (共同第一作者)
10. Feng Y, Peng Y, Jie J*, Yang Y*, Yang P*. The immune microenvironment and tissue engineering strategies for spinal cord regeneration. Frontiers in cellular neuroscience 2022; 16: 969002. (通讯作者)