贺倩茹*

发布时间:2015-05-01 浏览次数:3662


贺倩茹医学博士,副研究员,硕士生导师,美国杜克大学博士后。主要研究方向为周围神经损伤的修复。科研成果:近年来主持国家自然科学基金青年基金和面上项目国家高技术研究发展计划(863计划)子课题、江苏省高校自然科学研究面上项目和重大项目等。近五年在Bioact Mater., J Clin Invest.Sci Transl Med.NeuronExp Neurol.J Proteome Res.等高质量期刊发表论文十余篇。担任Neural Regen Res.Front Cell Neurosci.等杂志评审编辑。教学成果:主讲医学院PBL课程和病理学等课程。曾获南通大学第七届青年教师讲课比赛一等奖“南通大学第九届微课教学比赛二等奖”、“南通大学第十届微课教学比赛二等奖”、“南通大学本科教学工作审核评估先进个人”和南通大学医学院专项工作先进“服务地方之星”。指导硕士研究生参加江苏省研究生医学显微成像科研创新实践大赛分获二等奖和三等奖

研究方向主要科研工作:

1. 神经成纤维细胞在周围神经再生中的作用与机制研究;

2. 神经与肿瘤的互作机制。

代表性论文(第一及通迅作者):

1. Dingding Shen#, Jiahui He#, Miaomei Yu#, Zhenghang Cheng, Jingya Liu, Yue Zhao, Shiran Wang, Ruoyu Pei, Fei Ding*, Qianru He*, Chitosan-based nerve guidance conduits functionalized with fibroblast-derived extracellular vesicles promote peripheral nerve regeneration via miR-143-3p delivery. Bioact Mater., 2026, 553-572.

2. Ouyang Chen#, Qianru He#, Qingjian Han#, Kenta Furutani, Yun Gu, Madelynne Olexa, and Ru-Rong Ji*. Mechanisms and treatments of neuropathic itch in a mouse model of lymphoma. J Clin Invest., 2023, 133(4):e160807.

3. Qianru He#, Zhenghang Cheng#, Qiang Zhou, Fang Tong, Yan Li, Xinyang Zhou, Miaomei Yu, Yuhua Ji, Fei Ding*. Sensory and motor fibroblasts have different protein expression patterns and exert different growth promoting effects on sensory and motor neurons. Exp Neurol., 2023, 361:114314.

4. Yan Li#, Zhenghang Cheng#, Fanhui Yu, Qi Zhang, Shu Yu, Fei Ding*, Qianru He*. Activin A secreted from peripheral nerve fibroblasts promotes proliferation and migration of Schwann cells. Front Mol Neurosci., 2022, 15:859349.

5.  Qianru He#, Meng Cong#, Fanhui Yu, Yuhua Ji, Shu Yu, Haiyan Shi, Fei Ding*. Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons. Neural Regen Res., 2022, 17(8):1833-1840.

6. Qianru He#, Fanhui Yu#, Meng Cong, Yuhua Ji, Qi Zhang, Fei Ding*. Comparative Proteomic Analysis of Differentially Expressed Proteins between Injured Sensory and Motor Nerves after Peripheral Nerve Transection. J Proteome Res., 2021, 20(3):1488-1508.

7. Jasmine Ji#, Qianru He#, Xin Luo, Sangsu Bang, Yutaka Matsuoka, Aidan McGinnis, Andrea G. Nackley, Ru-Rong Ji*. IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice. Front. Immunol., 2021, 12, 787565.

8. Fang Tong#, Qianru He#, Wan-Jie Du, Huan Yang, Dongping Du, Shaofeng Pu*, Qingjian Han*. Sympathetic Nerve Mediated Spinal Glia Activation Underlies Itch in a Cutaneous T-Cell Lymphoma Model. Neurosci. Bull. 2021, doi: 10.1007/s12264-021-00805-6.

9. Qianru He#, Mi Shen#, Fang Tong, Meng Cong, Shibo Zhang, Yanpei Gong*, Fei Ding*. Differential Gene Expression in Primary Cultured Sensory and Motor Nerve Fibroblasts. Front Neurosci., 2019, 12, 1016.