贺倩茹

发布时间:2015-05-01 浏览次数:22

贺倩茹,医学博士,副研究员,硕士生导师,美国杜克大学博士后。主要研究方向为周围神经损伤的修复。科研成果:近年来主持国家自然科学基金、国家高技术研究发展计划(863计划)子课题、江苏省高校自然科学研究面上项目和重大项目等。近五年在J Clin Invest.Sci Transl Med.Neuron,Exp Neurol.,J Proteome Res.等高质量期刊发表论文十余篇。担任Frontiers in Pain Mechanisms 客座副主编。教学成果:讲授医学院PBL课程、医学遗传学、神经生物学和分子生物学技术等课程。曾获南通大学第七届青年教师讲课比赛一等奖南通大学本科教学工作审核评估先进个人。指导硕士研究生参加江苏省研究生医学显微成像科研创新实践大赛分获二等奖和三等奖。

科研方向:1. 神经成纤维细胞在周围神经再生中的作用与机制研究;2. 周围感觉与运动神经特异性再生的机制研究。

E-mail: heqianru@ntu.edu.cn

代表性论文:

1. Ouyang Chen#, Qianru He#, Qingjian Han#, Kenta Furutani, Yun Gu, Madelynne Olexa, and Ru-Rong Ji*. Mechanisms and treatments of neuropathic itch in a mouse model of lymphoma. J Clin Invest., 2023, 133(4):e160807.

2. Qianru He#, Zhenghang Cheng#, Qiang Zhou, Fang Tong, Yan Li, Xinyang Zhou, Miaomei Yu, Yuhua Ji, Fei Ding*. Sensory and motor fibroblasts have different protein expression patterns and exert different growth promoting effects on sensory and motor neurons. Exp Neurol., 2023, 361:114314.

3. Yan Li#, Zhenghang Cheng#, Fanhui Yu, Qi Zhang, Shu Yu, Fei Ding*, Qianru He*. Activin A secreted from peripheral nerve fibroblasts promotes proliferation and migration of Schwann cells. Front Mol Neurosci., 2022, 15:859349.

4.  Qianru He#, Meng Cong#, Fanhui Yu, Yuhua Ji, Shu Yu, Haiyan Shi, Fei Ding*. Peripheral nerve fibroblasts secrete neurotrophic factors to promote axon growth of motoneurons. Neural Regen Res., 2022, 17(8):1833-1840.

5. Qianru He#, Fanhui Yu#, Meng Cong, Yuhua Ji, Qi Zhang, Fei Ding*. Comparative Proteomic Analysis of Differentially Expressed Proteins between Injured Sensory and Motor Nerves after Peripheral Nerve Transection. J Proteome Res., 2021, 20(3):1488-1508.

6.  Jasmine Ji#, Qianru He#, Xin Luo, Sangsu Bang, Yutaka Matsuoka, Aidan McGinnis, Andrea G. Nackley, Ru-Rong Ji*. IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice. Front. Immunol., 2021, 12, 787565.

7.  Fang Tong#, Qianru He#, Wan-Jie Du, Huan Yang, Dongping Du, Shaofeng Pu*, Qingjian Han*. Sympathetic Nerve Mediated Spinal Glia Activation Underlies Itch in a Cutaneous T-Cell Lymphoma Model. Neurosci. Bull. 2021, doi: 10.1007/s12264-021-00805-6.

8.  Zilong Wang#, Changyu Jiang#, Qianru He, Megumi Matsuda, Qingjian Han, Ru-Rong Ji*. Anti-PD-1 treatment impairs opioid analgesia in rodents and nonhuman primates. Sci Transl Med., 2020, 12(531): eaaw6471.

9.  Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee*. Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel. Neuron, 2020, 105(5):882-894.

10. Qianru He#, Mi Shen#, Fang Tong, Meng Cong, Shibo Zhang, Yanpei Gong*, Fei Ding*. Differential Gene Expression in Primary Cultured Sensory and Motor Nerve Fibroblasts. Front Neurosci., 2019, 12, 1016.