程 琼

发布时间:2018-06-04 浏览次数:3206


程琼,女,医学博士,教授,硕士生导师,美国宾夕法尼亚州立大学访问学者。中国解剖学会会员、江苏省药物研究与开发协会会员、江苏省神经科学学会会员、中国研究型医院学会神经再生与修复专业委员会委员。

专业研究领域

1、脑卒中的神经炎症病理机制及干预研究

2、天然产物类神经保护剂的开发及药理作用研究

3、肿瘤微环境中施万细胞对肿瘤侵袭的作用机制研究  

专著与论集

参编专著《神经再生》,副主编江苏省高等学校重点教材《神经生物学》(2021-1-019

学术论文

1. Wang H, Li J, Zhang H, Wang M, Xiao L, Wang Y, Cheng Q*. Regulation of microglia polarization after cerebral ischemia. Front Cell Neurosci. 2023,17:1182621.

2. Cheng Q, Wang M, Jin R, Li G. Blocking of PI3-kinase beta protects against cerebral ischemia/reperfusion injury by reducing platelet activation and downstream microvascular thrombosis in rats. Sci Rep. 2023,13(1):2030.

3. Zhou Y, Liu F, Ma C, Cheng Q*. Involvement of microRNAs and their potential diagnostic, therapeutic, and prognostic role in hepatocellular carcinoma. J Clin Lab Anal. 2022,36(10):e24673.

4. Sun H, Li M, Ji Y, Zhu J, Chen Z, Zhang L, Deng C, Cheng Q, Wang W, Shen Y, Shen D. Identification of regulatory factors and prognostic markers in Amyotrophic Lateral Sclerosis. Antioxidants (Basel). 2022,11(2):303.

5. Wang Y, Ge X, Yu S, Cheng Q*. Achyranthes bidentata polypeptide alleviates neurotoxicity of lipopolysaccharide-activated microglia via PI3K/Akt dependent NOX2/ROS pathway. Ann Transl Med. 2021,9(20):1522.

6. Cheng Q#, Chen J#, Guo H, Lu JL, Zhou J, Guo XY, Shi Y, Zhang Y, Yu S, Zhang Q*, Ding F*. Pyrroloquinoline quinone promotes mitochondrial biogenesis in rotenone-induced Parkinson's disease model via AMPK activation. Acta Pharmacol Sin. 2021,42(5):665.

7. Ding F#, Bai Y#, Cheng Q#, Yu S#, Cheng M, Wu Y, Zhang X*, Liang X*, Gu X*. Bidentatide, a novel plant peptide derived from Achyranthes bidentata blume: isolation, characterization, and neuroprotection through inhibition of NR2B-containing NMDA receptors. Int J Mol Sci. 2021,22(15):7977.

8. Ge X, Wang Y, Yu S, Cao X, Chen Y, Cheng Q*, Ding F*. Anti-inflammatory Activity of a polypeptide fraction from Achyranthes bidentate in Amyloid β oligomers induced model of Alzheimer's disease. Front Pharmacol. 2021,12:716177.

9. Zhang Q, Zhou J, Shen M, Xu H, Yu S, Cheng Q*, Ding F*. Pyrroloquinoline Quinone inhibits rotenone-induced microglia inflammation by enhancing autophagy. Molecules. 2020,25(19):4359.

10. Cheng Q, Shen Y, Cheng Z, Shao Q, Wang C, Sun H, Zhang Q. Achyranthes bidentata polypeptide k suppresses neuroinflammation in BV2 microglia through Nrf2-dependent mechanism. Ann Transl Med. 2019,7(20):575.

11. Cheng Q#, Tong F#, Shen Y, He C, Wang C, Ding F. Achyranthes bidentata polypeptide k improves long-term neurological outcomes through reducing downstream microvascular thrombosis in experimental ischemic stroke. Brain Res. 2019,1706:166.

12. Cheng Q, Wang YX, Yu J, Yi S. Critical signaling pathways during Wallerian degeneration of peripheral nerve. Neural Regen Res. 2017,12(6):995.

  主要科研项目

近年来主持国家自然科学基金两项、江苏省高校自然科学研究重大项目及面上项目、南通市科技项目等,发表SCI论文十余篇,获中国发明专利授权两项。

讲授课程 

主讲神经生物学、再生医学等本科课程,及研究生现代神经生物学、神经科学研究进展等课程。曾获南通大学第二届青年教师讲课比赛二等奖、江苏省高等教育教学成果二等奖。

指导研究生情况

指导硕士研究生参加“江苏省研究生医学显微成像科研创新实践大赛”获二等奖。

  电子信箱:cq1981@ntu.edu.cn