顾晓松,男,(1953.12.2——),医学组织工程学与神经再生专家,江苏省南通市人。1980年毕业于南通医学院,1998年获复旦大学(原上海医科大学)医学博士学位。现任南通大学江苏省神经再生重点实验室主任,中国生物医学工程学会副理事长,中国解剖学会名誉理事长。曾任南通医学院院长,南通大学校长、党委书记。
顾晓松教授长期从事组织工程神经与神经再生研究,获首届国家杰出青年科学基金。提出“构建生物可降解组织工程神经”的学术观点,被载入英国剑桥大学教科书;发明构建组织工程神经的新技术和新工艺;发明生物可降解人工神经移植物,在国际上率先将壳聚糖人工神经移植物应用于临床,为我国组织工程神经研究与转化走在国际前沿作出了突出贡献。获国家技术发明二等奖,江苏省科学技术进步一等奖。获2014年度何梁何利科学与技术进步奖。
2015年当选中国工程院院士。
代表作:
1. He J, Sun C, Gu Z, Yang Y, Gu M, Xue C, Xie Z, Ren H, Wang Y, Liu Y, Liu M, Ding F, Leong KW, Gu X. Morphology, Migration, and Transcriptome Analysis of Schwann Cell Culture on Butterfly Wings with Different Surface Architectures. ACS Nano. 2018; 12(10):9660-9668. doi:10.1021/acsnano.8b00552(通讯作者)
2. Chen B, Li Y, Yu B, Zhang Z, Brommer B, Williams PR, Liu Y, Hegarty SV, Zhou S, Zhu J, Guo H, Lu Y, Zhang Y, Gu X, He Z. Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations. Cell. 2018; 174(3):521-535 e513. doi:10.1016/j.cell.2018.06.005(通讯作者)
3. Tang X, Qin H, Gu X, Fu X. China's landscape in regenerative medicine. Biomaterials. 2017; 124:78-94. doi:10.1016/j.biomaterials.2017.01.044(通讯作者)
4. Liu Y, Zhou Q, Wang Y, Luo L, Yang J, Yang L, Liu M, Li Y, Qian T, Zheng Y, Li M, Li J, Gu Y, Han Z, Xu M, Wang Y, Zhu C, Yu B, Yang Y, Ding F, Jiang J, Yang H, Gu X. Gekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration. Nat Commun. 2015; 6:10033. doi:10.1038/ncomms10033(通讯作者)
5. Yu B, Zhou S, Yi S, Gu X. The regulatory roles of non-coding RNAs in nerve injury and regeneration. Prog Neurobiol. 2015; 134:122-139. doi:10.1016/j.pneurobio.2015.09.006(通讯作者)
6. Li S, Xue C, Yuan Y, Zhang R, Wang Y, Wang Y, Yu B, Liu J, Ding F, Yang Y, Gu X. The transcriptional landscape of dorsal root ganglia after sciatic nerve transection. Sci Rep. 2015; 5:16888. doi:10.1038/srep16888(通讯作者)
7. Gu X, Ding F, Williams DF. Neural tissue engineering options for peripheral nerve regeneration. Biomaterials. 2014; 35(24):6143-6156. doi:10.1016/j.biomaterials.2014.04.064(通讯作者)
8. Sun C, Wang M, Liu X, Luo L, Li K, Zhang S, Wang Y, Yang Y, Ding F, Gu X. PCAF improves glucose homeostasis by suppressing the gluconeogenic activity of PGC-1alpha. Cell Rep. 2014; 9(6):2250-2262. doi:10.1016/j.celrep.2014.11.029(通讯作者)
9. Yu B, Qian T, Wang Y, Zhou S, Ding G, Ding F, Gu X. miR-182 inhibits Schwann cell proliferation and migration by targeting FGF9 and NTM, respectively at an early stage following sciatic nerve injury. Nucleic Acids Res. 2012; 40(20):10356-10365. doi:10.1093/nar/gks750(通讯作者)
10. Gu X, Ding F, Yang Y, Liu J. Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration. Prog Neurobiol. 2011; 93(2):204-230. doi:10.1016/j.pneurobio.2010.11.002
11. Yang Y, Ding F, Wu J, Hu W, Liu W, Liu J, Gu X. Development and evaluation of silk fibroin-based nerve grafts used for peripheral nerve regeneration. Biomaterials. 2007; 28(36):5526-5535. doi:10.1016/j.biomaterials.2007.09.001(通讯作者)
12. Wang X, Hu W, Cao Y, Yao J, Wu J, Gu X. Dog sciatic nerve regeneration across a 30-mm defect bridged by a chitosan/PGA artificial nerve graft. Brain. 2005; 128(Pt 8):1897-1910. doi:10.1093/brain/awh517(通讯作者)