孙诚，教授，博士生导师。2004年获南京大学理学博士学位，随后于中科院上海生命科学研究院、哈佛大学医学院进行博士后研究。2011年起任职于南通大学神经再生重点实验室，主要研究领域涉及神经退行性疾病、慢性代谢性疾病及肿瘤生物学等。以为第一发明人获中国发明专利6项，澳大利亚标准专利3项，欧亚专利1项。先后主持科技部重点研发计划课题1项，国家自然科学基金面上项目5项。2013年获上海市科学技术奖（自然科学）二等奖（排名3），2014年获江苏省“青蓝工程”中青年学术带头人，2016年获江苏省“六大人才”高峰计划资助，2018遴选为江苏省“333”高层次人才培养对象，2019年获江苏省科学技术奖三等奖（排名2）。现为中国病理生理学会内分泌与代谢专业委员会委员。邮箱：suncheng1975@ntu.edu.cn
代表性论文（通讯作者）：
1. Wu Y#, Ma J#, Chen J, Liu X, Wang Z, Luo L*, Sun C*. Ablation of CD44 attenuates adipogenesis in white adipocytes via the tryptophan 5-hydroxylase 2/5-hydroxytryptamine axis to protect mice from high-fat diet-induced obesity. Am J Pathol 2025, 195(2): 247-264.
2. Ju Q, Sheng W, Zhang M, Chen J, Wu L, Liu X, Fang W*, Shi H*, Sun C*. TAK1-mediated phosphorylation of PLCE1 represses PIP2 hydrolysis to impede esophageal squamous cancer metastasis.eLife2025, 13: RP97373.
3. Ma J, Wu Y, Cen L, Wang Z, Jiang K, Lian B*, Sun C*. Cold-inducible lncRNA266 promotes browning and the thermogenic program in white adipose tissue. EMBO Reports 2023, e55467.
4. Lian B#, Zhang J#, Yin X, Wang J, Li L, Ju Q, Wang Y, Jiang Y, Liu X, Chen Y*, Tang X*,Sun C*. SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2.Cell Rep Med2024, 5(8): 101684.
5. Wang Y#, Li L#, Wu Y, Zhang S, Ju Q, Yang Y, Jin Y*, Shi H*, Sun C*. CD44 deficiency represses neuroinflammation and rescues dopaminergic neurons in a mouse model of Parkinson’s disease. Pharmacol Res 2022, 177: 106133.
6. Ma J, Wang Y, Ding J, Zhang S, Yang Y, Sun C*. SAHA induces white fat browning and rectifies dysfunctions via activation of ZFPs. J Endocrinol2021, 249(3): 177-193.
7. Li B#, Yang Y#, Wang Y, Zhang J, Ding J, Liu X, Jin Y, Lian B*, Ling Y*, Sun C*. Acetylation of NDUFV1 induced by a newly synthesized HDAC6 inhibitor HGC rescues dopaminergic neuron loss in Parkinson models. iScience 2021, 24: 102302. (Lead Contact)
8. Shi H#, Ju Q#, Mao Y, Wang Y, Ding J, Liu X, Tang X*, Sun C*. TAK1 phosphorylates RASSF9 and inhibits esophageal squamous tumor cell proliferation by targeting the RAS/MEK/ERK axis. Adv Sci 2021, 8(5): 202001575.
9. Nie L#, Yuan XL#, Jiang KT, Jiang YH, Yuan J, Luo L, Cui SW*, Sun C*. Salsalate activates skeletal muscle thermogenesis and protects mice from high fat diet induced metabolic dysfunction. eBioMedicine 2017, 23: 136-145.
10. Sun C*, Wang M, Liu X, Luo L, Li K, Zhang S, Wang Y, Yang Y, Ding F, Gu X*. PCAF improves glucose homeostasis by suppressing the gluconeogenic activity of PGC-1a. Cell Rep2014, 9(6): 2250-2262. (Lead Contact)
