张 琦

发布时间:2020-04-22 浏览次数:4970


   

      张琦,博士,教授,博士生导师。美国Vanderbilt大学博士后。主要研究方向为神经损伤修复,近年来主持国家自然科学基金、江苏省自然科学基金、江苏省高校自然科学研究项目等。讲授神经生物学、再生医学、细胞生物学和分子生物学等课程。入选江苏省青蓝工程优秀青年骨干教师,南通市226人才第二层次培养对象。中国解剖学会神经再生医学分会委员,江苏省神经科学学会理事。

研究方向1. 遗传性癫痫的发病机制;

  2. 靶向线粒体功能障碍的帕金森病治疗策略。

邮箱:zhangqi@ntu.edu.cn

代表性论文:

(1)  Wenpeng Liang#, Jie Wang#, Jiahui Sui, Feng Yun, Yuntian Shen, Jing Zhou, Youjia Wu, Dingding Shen*, Qi Zhang*. Inflammation as a target for the treatment of fever-associated epilepsy in zebrafish larvae. Int Immunopharmacol, 2023, 116: 109802.

(2)  Jing Zhou, Wenpeng Liang, Jie Wang, Juan Chen, Dong Liu, Xin Wang, Youjia Wu, Qi Zhang*, Dingding Shen*. An epileptic encephalopathy associated GABRG2 missense mutation leads to pre- and postsynaptic defects in zebrafish. Hum Mol Genet, 2022; 31(19): 3216-3230.

(3)  Qiong Cheng, Juan Chen, Hui Guo, Jin-Li Lu, Jing Zhou, Xin-Yu Guo, Yue Shi, Yu Zhang, Shu Yu, Qi Zhang*, Fei Ding*. Pyrroloquinoline quinone promotes mitochondrial biogenesis in rotenone-induced Parkinson's disease model via AMPK activation. Acta Pharmacol Sin, 2021, 42(5): 665-678.

(4)   Yi-Wu Shi#; Qi Zhang#; Kefu Cai#; Sarah Poliquin; Wangzhen Shen; Nathan Winters; Yong-Hong Yi; Jie Wang; Ningning Hu; Robert L Macdonald; Wei-Ping Liao; Jing-Qiong Kang*. Synaptic Clustering Differences Due to Different GABRB3 Mutations Cause Variable Epilepsy Syndromes. Brain, 2019, 142(10): 3028-3044.

(5)    Qi Zhang; Shuhua Chen; Shu Yu; Jiaojiao Qin; Jingjing Zhang; Qiong Cheng; Kaifu Ke; Fei Ding*. Neuroprotective effects of pyrroloquinoline quinone against rotenone injury in primary cultured midbrain neurons and in a rat model of Parkinson's disease. Neuropharmacology, 2016, 108: 238-251.