顾芸，教授，博士生导师，田纳西州大学及杜克大学访问学者。长期致力于周围神经损伤与再生以及组织工程与神经再生领域的研究。曾担任国家重点研发计划子课题南通大学负责人，主持国家自然科学基金面上项目，国家自然科学青年项目，江苏省自然科学基金面上项目，江苏省高校自然科学研究重大项目及江苏省高校自然科学研究面上项目。入选江苏省“青蓝工程学术带头人”及南通市“226第二层次人才”，获江苏省科学技术三等奖。现任中国生物材料学会神经修复分会理事，并担任《Frontiers in Cellular Neuropathology》期刊编委。
科研方向为神经损伤修复（周围与中枢）以及神经病理性疼痛。
Email: guyun@ntu.edu.cn
近5年代表性论文：
1. Cai J, Li H, Chen L, Luo L, Wu X, Yuan M, Han M, Wen S, Zhu C, Gu Y. Gnao1 acts as a gatekeeper to alleviate neuropathic pain by silencing pro-nociceptive signaling cascades. J Headache Pain (2026). doi:10.1186/s10194-026-02436-6 (通讯作者).
2. Xu J, Peng Q, Cai J, Shangguan J, Su W, Chen G, Sun H, Zhu C, Gu Y (2024) The Schwann cell-specific G-protein Galphao (Gnao1) is a cell-intrinsic controller contributing to the regulation of myelination in peripheral nerve system. Acta Neuropathol Commun 12 (1):24. doi:10.1186/s40478-024-01720-3 (通讯作者)..
3. Xu J, Zhang B, Cai J, Peng Q, Hu J, Askar P, Shangguan J, Su W, Zhu C, Sun H, Zhou S, Chen G, Yang X, Gu Y (2023) The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration. Mol Med 29 (1):79. doi:10.1186/s10020-023-00667-w (通讯作者)..
4. Gong L#, Gu Y#, Han X, Luan C, Liu C, Wang X, Sun Y, Zheng M, Fang M, Yang S, Xu L, Sun H, Yu B, Gu X, Zhou S (2023) Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord Injury. Neurosci Bull 39 (2):213-244. doi:10.1007/s12264-022-00897-8 (#共同第一作者).
5. Wang S, Zhu C, Zhang B, Hu J, Xu J, Xue C, Bao S, Gu X, Ding F, Yang Y, Gu X and Gu Y. BMSC-derived extracellular matrix better optimizes the microenvironment to support nerve regeneration. Biomaterials (2022), 280:121251 (通讯作者).
6. Zhang B, Su W, Hu J, Xu J, Askar P, Bao S, Zhou S, Chen G and Gu Y. Transcriptome Analysis of Schwann Cells at Various Stages of Myelination Implicates Chromatin Regulator Sin3A in Control of Myelination Identity. Neuroscience bulletin (2022), 38:720-740. (通讯作者)
7. Askar P, Xu J, Hu J, Shangguan J, Sun H, Zhou S, Yang X, Chen G, Su W and Gu Y. The Etv1/Er81 transcription factor coordinates myelination-related genes to regulate Schwann cell differentiation and myelination. Annals of Translational Medicine (2022), 10:875. (通讯作者)
8. Hu JX, Shangguan JH, Askar P, Xu JH, Sun HL, Zhou SL, Zhu CL, Su WF and Gu Y. Decellularization alters the unfavorable regenerative adverse microenvironment of the injured spinal cord to support neurite outgrowth. Annals of Translational Medicine (2022). (通讯作者)
9. Wang K#, Gu Y#, Liao Y, Bang S, Donnelly CR, Chen O, Tao X, Mirando AJ, Hilton MJ and Ji RR. PD-1 blockade inhibits osteoclast formation and murine bone cancer pain. J Clin Invest (2020), 130:3603-3620. (#共同第一作者)
