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陈 罡

发布者:神经再生重点实验室 发布时间:2015-11-17 游览次数:

陈罡,江苏省特聘教授,教育部新世纪优秀人才。中国科学院神经科学研究所博士,曾任美国哈佛大学医学院、杜克大学医学中心博士后、美国杜克大学助理教授,入选江苏省“333”人才工程,江苏省青蓝工程,江苏省高校优秀共产党员,南通市青年岗位能手,南通大学我最喜爱的老师等。现任江苏省神经科学学会理事,江苏省神经科学学会青年工作委员会副主任委员,江苏高校优秀科技创新团队(神经损伤与功能恢复)的带头人。承担国家自然科学基金、江苏省自然科学基金、江苏省高校自然科学重大项目等课题。已发表SCI收录论文27篇,其中第一作者或通讯联系人12篇,影响因子大于10的有5篇。曾获江苏省科技进步二等奖。

代表性论文* 第一作者,# 通讯作者)

1. Yul Huh, Ru-Rong Ji , Gang Chen#. Neuroinflammation, bone marrow stemcells, and chronic pain. Front. Immunol.2017,8:1014.Review

2. GangChen*, Yong Ho Kim*, Hui Li, Hao Luo, Da-Lu Liu, Zhi-Jun Zhang,MarkLay, Wonseok Chang, Yu-Qiu Zhang and Ru-Rong Ji. PD-L1 inhibits acuteandchronic pain by suppressing nociceptive neuron activity via PD-1.NatureNeuroscience.2017,20: 917-926.

This article washighlighted by Nature and Nature Neuroscience (2017, 20:897-899).

3.Gang Chen#,Xin Luo, M Yawar Qadri, Temugin Berta, andRu-Rong Ji.Sex-dependentglialsignaling in pathological pain: Distinct role of spinal microglia andastrocytes.Neuroscience Bulletin.2017.June 5. Doi:10.1007/s12264-017-0145-y.

4.Chen G*, XieRG*,Gao YJ*, Xu ZZ*, Zhao LX, BangSB, Berta T,Park CK, Lay M, Chen W, Ji RR.β-arrestin-2regulates NMDA receptorfunction inspinal lamina II neurons and duration of persistent pain.Nature Communications 7, Articlenumber: 12531(2016) doi:10.1038/ncomms12531.

5.BertaT*, Qadri Y.J.*,Chen G*, Ji RR. MicroglialSignaling inChronic Pain with a Special Focus on Caspase 6, p38 MAPKinase, andSexDependence.J Dent Res.2016Jun 15. pii: 0022034516653604.Review

6.ShenYT,Gu Y, Su WF, Zhong JF, Jin ZH, Gu XS,ChenG#.Rab27b is involved in lysosomal exocytosis and proteolipid proteintraffickingin oligodendrocytes.NeuroscienceBulletin.2016.August; 32 (4):331-340.Coverstory

7. Su WF, Gu Y, Wei ZY, Shen YT,Jin ZH, Yuan Y, Gu XS,Chen G#. Rab27a/Slp2-acomplex is involved in Schwann cell myelination.Neural Regeneration Research.2016, 11(11):1830-1838.

8.ShenYT, Yuan Y, SuWF, Gu Y,ChenG#.Therolesof lysosomal exocytosis in regulated myelination. J Neurol Neuromed.2016,1(5):4-8.Review

9.ChenG#,ParkCK,Xie RG,Ji RR. Intrathecal bone marrow stromal cells inhibitneuropathicpain viaTGF-b secretion.The Journal of Clinical Investigation.2015;125(8):3226-3240

10.ChenG,Park CK, Xie RG, BertaT, Nedergaard M, Ji RR.Connexin-43 induceschemokine releasefrom spinal cord astrocytes to maintain late-phaseneuropathic pain in mice.Brain.2014 Aug;137(Pt 8):2193-2209.

11.ChenG#,ZhangZ J, Wei Z Y, Cheng Q, Li X, Li W, Duan S M, Gu X S. Lysosomalexocytosis inSchwann cells contributes to axon remyelination.Glia.2012,60(2): 295-305.

12.Zhang Z*,Chen G*, Zhou W*,SongA, Xu T, Luo Q, Wang W, Gu XS, Duan S.Regulated ATPrelease from astrocytes through lysosome exocytosis.NatCellBiol.2007,9:945-953.

13.Chen G,Li HM, Chen YR, Gu XS, Duan S.Decreased estradiol release from astrocytes contributes totheneurodegeneration in a mouse model of Niemann-Pick disease type C.Glia.2007,55:1509-1518.